Tissue engineering and regenerative medicine are both elements in my scientific thriller, THE LIFE AFTER LIFE CONSPIRACY. Though the book is finished, I still to keep up with the new findings in labs --- mainly (to be modest, and honest!) for the satisfaction of seeing ideas I'd predicted coming about in the real world.
In another post here recently, I picked up a Wall Street Journal report on a replacement windpipe grown from the patient's own cells, using a scaffold as a kind of framework for the cells to grow into shape. That is just one instance of tissue engineering breakthroughs using scaffolds and a patient's own cells ("pluripotent stem cells," in the jargon of regenerative medicine).
This week, Mo Costandi in his blog Neurophilosophy, which appears in the British newspaper The Guardian, reports on a different breakthrough: using pluripotent stem cells to grow replacement body parts without the use of a scaffold. That is, using 3 dimensional cultures to (among other things) ". . . to self-organize into functional brain tissue. . ."
"Growing a complete, functioning brain is unfeasible , but there is real potential in growing functional neural tissue . . . for transplantation into the human brain," Mo writes. ("Unfeasible" right now, I respond. But just wait.)
This article can be a bit technical for the layperson, but four short videos embedded in the piece make it make sense.